Why do I get Restless Leg Syndrome when I take Nyquil?

I get it when I take Nyquil or Tylenol PM. It's terrible because I am nearly asleep physically, my brain is shutting down and I can't keep my eyes open, but my legs feel like they're being electrocuted!

I don't get them any other time… Am I allergic?

****Certain medications-such as antinausea drugs (prochlorperazine or metoclopramide), antiseizure drugs (phenytoin or droperidol), antipsychotic drugs (haloperidol or phenothiazine derivatives), and some cold and allergy medications-may aggravate symptoms. Patients can talk with their physicians about the possibility of changing medications.******

Researchers also have found that caffeine, alcohol, and tobacco may aggravate or trigger symptoms in patients who are predisposed to develop RLS. Some studies have shown that a reduction or complete elimination of such substances may relieve symptoms, although it remains unclear whether elimination of such substances can prevent RLS symptoms from occurring at all.

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6 Responses to “Why do I get Restless Leg Syndrome when I take Nyquil?”

  1. Amanda P Says:

    dont take nyquil! DUH
    References :

  2. Andrea Says:

    ****Certain medications-such as antinausea drugs (prochlorperazine or metoclopramide), antiseizure drugs (phenytoin or droperidol), antipsychotic drugs (haloperidol or phenothiazine derivatives), and some cold and allergy medications-may aggravate symptoms. Patients can talk with their physicians about the possibility of changing medications.******

    Researchers also have found that caffeine, alcohol, and tobacco may aggravate or trigger symptoms in patients who are predisposed to develop RLS. Some studies have shown that a reduction or complete elimination of such substances may relieve symptoms, although it remains unclear whether elimination of such substances can prevent RLS symptoms from occurring at all.
    References :
    http://www.ninds.nih.gov/disorders/restless_legs/detail_restless_legs.htm#90963237

  3. MWestbrook Says:

    I get this, too! I never called it this, though. I understand that it's your body "relaxing" and all your muscles are involuntarily "going to sleep," but your body is still tense, hence the twitches and pins and needles and zaps. It's like your brain going to sleep before everything gets a chance to settle down.
    References :

  4. smiillee Says:

    NYQUIL USUALLY PUT YOU TO SLEEP. RLS USUALLY ACT UP WHEN IT'S TIME TO RELAX, SO THAT COULD BE THE PROBLEM.
    References :

  5. pauline c Says:

    Probably not allergic but take this reference http://www.drugs.com/mtm/nyquil-liquicap.html scroll down to What are the possible side effects of acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine? so more than likely its a side effect
    References :

  6. ineedacar Says:

    most pepole agree that restless leg syndrome is a mental trick used to make pepole think theres something wrong with them.
    think about it for a minute… your saying two compleately difrent chemical compounds are causing a reaction that effects your centrel nervios system but only in your legs… odes that sound right? its your imagination but if it helps i hear m&ms will help… not really but if you beleve they will then 2 a night will do ya
    References :
    there was no restless leg syndrome untill mid 2006 so think to yourself "am i just imaging this?"

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